Fig. 4. Epistasis analysis with pipe reveals that ik2 acts
upstream of the Toll-Dorsal pathway during oogenesis. (A-D)
Dark-field views of larval cuticle preparations at the end of embryogenesis
from (A) wild type, (B) a bicaudal embryo from an ik21
germline clone female, (C) a dorsalized embryo from a
pipe1 mutant female and (D) a dorsalized embryo from a
ik21; pipe1 double homozygous mutant
female.