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Figure 3


Fig. 3. wnt and vps-35 mutants have ALM polarity defects. (A) Wild-type mec-4::gfp; ALM has a long anterior process. (B) cwn-1; cwn-2; ALM with a symmetric polarity. Arrows indicate the long anterior and posterior processes. (C) vps-35; ALM with a reversed polarity, PVM migrates anteriorly rather than posteriorly and is found near ALM (see text for details). (D) ALM and PLM cell bodies and process trajectories; boxed area indicates region shown in fluorescence photomicrographs. Anterior is leftwards; dorsal is towards the top.