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Figure 1


Fig. 1. Fgf8 hypomorphic (Null/Neo) and telencephalon null (TelKO) mutants are hypoplastic and have morphological defects in rostral and midline regions of the telencephalon. (A-E'') Horizontal sections of E14.5 wild-type (A-E), Fgf8Null/Neo (A'-E') and Fgf8TelKO (A''-E'') brains were stained with Cresyl Violet. Structures were defined by their location and morphology. A,A',A'' are most dorsal and E,E',E'' are most ventral. A, amygdala region; A*, mutant amygdala region; GE*, mutant ganglionic eminence region; LGE, lateral ganglionic eminence; MGE, medial ganglionic eminence; OB, olfactory bulb; S, septum.