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Figure 4


Fig. 4. Analysis of proliferation in the Fgf8 mutants at E9.0. Anti-phosphohistone3 (PH3) immunofluorescence on horizontal sections through the forebrain labels the nuclei of mitotic cells in wild-type (A-E), Fgf8Null/Neo (A'-E') and Fgf8TelKO (A''-E'') embryos. A-A'' are the most ventral; E-E'' are the most dorsal. Note, sections B,B',B'' are the same as in Fig. 3. Os, optic stalk; Tel, telencephalon.