Fig. 9. Fgf8 mutants lose ventral molecular properties in the telencephalon. In situ hybridization on coronal sections from E12.5 wild type, Fgf8^Null/Neo and Fgf8^TelKO embryos showing Pax6 (A-A''), Tbr1 (B-B''), Shh (C-C''), Nkx2.1 (D-D''), Dlx2 (E-E'') and Dlx5 (F-F'') expression. Horizontal arrows in A' and E'' indicate the approximate pallial-subpallial boundary in the Fgf8^TelKO mutant. Also note the divergent morphology of the dorsal midline tissues in the Fgf8^Null/Neo and Fgf8^TelKO mutants (vertical arrows in B',B''). CX, cortex; LGE, lateral ganglionic eminence; MGE, medial ganglionic eminence; S, septum; SP^*, unspecified subpallium.