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Figure 6


Fig. 6. HLH-1 functions redundantly with FOZI-1 and MAB-5 to specify M-derived BWMs. (A,B) Quantification of the number of SM-like cells (expressing hlh-8::gfp) (A) and M-derived BWMs (expressing myo-3::gfp) (B). n values are given for each genotype scored. Mean values are shown with error bars representing standard deviation for each sample set. All animals showed normal proliferation in the early M lineage up to the 16-M stage. The number of SM-like cells and M-derived BWMs were also scored in the following animals: mab-5(RNAi), hlh-1(RNAi), hlh-1(RNAi); mab-5(e1239), hlh-1(RNAi); fozi-1(cc609), hlh-1(RNAi); fozi-1(cc609) mab-5(RNAi) and hlh-1(cc561ts+RNAi); fozi-1(cc609) mab-5(e1239). For each genotype, more than 50 animals were scored for the number of SMs and more than ten animals were scored for the number of M-derived BWMs. *A small percentage of these animals lacked all M-derived BWMs and had a total of 16-18 SM-like cells.