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Figure 1


Fig. 1. Ptpmeg homologs, locus structure and mutations. (A) Drosophila and human Ptpmeg family proteins. The ptpmeg1 mutation is indicated. (B) ptpmeg locus with the major transcripts, ptpmeg2 insertion and ptpmeg1 mutation indicated. (C) Sequence trace showing ptpmeg1 mutation. (D) ptpmeg1 produces no detectable full-length Ptpmeg, whereas ptpmeg2 reduces Ptpmeg expression. Asterisk indicates background band. Elav is loading control.