Fig. 5. Loss of semaphorin signalling through neuropilins does not impair brain
vascularisation. Visualisation (A-D) and quantitation (E) of
vessel branching in 12.5 dpc mouse hindbrains. (E) Hindbrains with normal
neuropilin function (A) showed a similar amount of vessel branching per 0.25
mm2 as hindbrains lacking semaphorin signalling through NRP1 (B) or
NRP2 (C) or lacking both NRP2 and semaphorin signalling through NRP1 (D).