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Figure 5


Fig. 5. Loss of semaphorin signalling through neuropilins does not impair brain vascularisation. Visualisation (A-D) and quantitation (E) of vessel branching in 12.5 dpc mouse hindbrains. (E) Hindbrains with normal neuropilin function (A) showed a similar amount of vessel branching per 0.25 mm2 as hindbrains lacking semaphorin signalling through NRP1 (B) or NRP2 (C) or lacking both NRP2 and semaphorin signalling through NRP1 (D).