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Figure 6


Fig. 6. Apical markers are correctly localized in the lulu neural plate. (A-H) Immunofluorescence on transverse sections of E8.5 wild-type (WT; A,C,E,G) and lulu mutant (B,D,F,H) neural plates. (A,B) ZO-2 marks the tight junctions at the apical-basal border of the neuroepithelium. (C,D) N-cadherin marks adherens junctions. (E,F) Crumbs is restricted to the apical surface. (G,H) Pals1 is localized to the apical and apico-lateral domain. Dorsal is up in all panels. Scale bar: 10 µm in A,B; 5 µm in C-H.