Fig. 6. Ectopic expression of either Wnt5 or Wnt4 is sufficient to repel the salivary glands. (A-C) Lateral views of stage 16 Drosophila embryos stained for FKH and CRB. (B) WNT5 was ectopically expressed in the visceral mesoderm, dorsal to the gland (located above the gland in these panels). The misexpression of WNT5 is sufficient to redirect the tip of the salivary gland ventrally. (C) When Wnt4 is ectopically expressed in the visceral mesoderm, it is sufficient to repel the entire salivary gland away from the visceral mesoderm. These data support the hypothesis that both Wnt proteins act as repellents.