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Figure 5


Fig. 5. Mutations in the Drosophila lkb1 gene affect Mira localization at the NB basal pole. (A) Mira localization in wild-type, pinsP62/pinsP62 and dlkb1315/dlkb1315 NBs. Cells in metaphase and telophase were stained for tubulin (Tub), DNA and Mira. Scale bar: 5 µm. (B) Distribution of Mira in dividing NBs from wild-type (wt), dlkb1315/dlkb1315 and pinsP62/pinsP62 brains. Regular, regular Mira crescent at the basal pole; cortical, Mira associated with the entire cell cortex; diffuse, Mira dispersed in the cytoplasm.