Fig. 6. Mutations in the Drosophila lkb1 gene disrupt Baz/Par-6/DaPKC
but not Pins/G
i localization at the NB apical pole.
(A) Pins, G
i, Baz, Par-6 and DaPKC localization in wild-type and
dlkb1315/dlkb1315 mutants. NBs in the first row
were simultaneously stained for Pins, Centrosomin (Cnn) and DNA (blue). Cells
shown in the subsequent rows were stained for tubulin (Tub), DNA (blue) and
either G
i, Baz, Par-6 or DaPKC. Scale bar: 5 µm. (B)
Frequencies of NBs with Pins, G
i, Baz, Par-6 and DaPKC crescents in
wild-type and dlkb1315/dlkb1315 mutant
brains.