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Figure 5


Fig. 5. In situ hybridisation in the coronal sections from Cdk5+/+ and Cdk5-/- mouse embryos at E16.5 using Neurod1 and doublecortin probes. The expression of these genes in the premigratory zone of Cdk5-/- embryos was comparable to that in Cdk5+/+ embryos, indicating that initial neuronal differentiation is not disturbed in Cdk5-/- mice. P, pia; V, ventricle. Scale bars: 100 µm.