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Figure 9


Fig. 9. Defective dendritic development in CxCdk5KO mice. (A) Position and (B) detailed morphologies of layer V neurons in CxCdk5KO;YFP-H double-transgenic mice. (A) Typical examples of the cerebral cortex in coronal sections from control and CxCdk5KO mice at P14. Bin distributions of YFP-positive layer V neurons are shown (control, black; CxCdk5KO, grey). (B) Confocal images of the cerebral cortex of control (Cont.;YFP-H) and CxCdk5KO (CxCdk5KO;YFP-H) mice at P14. Abnormal dendritic structures (arrows) and axonal trajectories (arrowheads) are present in CxCdk5KO mice. Scale bar: 50 µm.