Fig. 5. Regulation of Cdx1 by Wnt3a. Expression of Cdx1 in
E8.5 wild-type (A,B), LRE mutant (C,D) and
LRE+RARE mutant (E,F) mouse embryos following ex vivo culture
with control (A,C,E) or Wnt3a-conditioned (B,D,F) media. Embryos of a given
genotype were cultured and stained in parallel. Mutants were stained four
times longer than controls to reveal residual expression of Cdx1.