Fig. 4. Cell proliferation in wild-type and mutant Drosophila lymph glands. (A,B) Lymph glands from wild-type (A) and Df(2R)SM206 (B) mid-third instar larvae stained for cells in S phase. Confocal section from the middle of the organ shows BrdU incorporation in cells of primary (I) and secondary (II) lobes. (C-E) Mitotic cells in the lymph glands from wild-type (C), Zfrp8^M-1-1 (D) and Df(2R)SM206 (E) mid-third instar larvae. Projection through 10 µm section of the organ shows cells with condensed DNA, stained with anti-H3P antibodies. Arrows point to areas with high mitotic activity. Scale bars: 70 µm.