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Figure 4


Fig. 4. Anteroposterior targeting shift in P15 Ac3-null mice. (A) Schematic diagram showing the medial portion of the right bulb. White dots correspond to the topographical glomerular coordinates innervated by M72-expressing OSNs. Blue dots indicate the innervation of M72-expressing OSNs in an Ac3-/- background. (B) Schematic showing a dorsal view of a left olfactory bulb. The color code is similar to that in A, and circles indicate lateral glomeruli. (C) Similar lateral view to that in A, but with coordinates corresponding to glomeruli innervated by MOR23-expressing OSNs. (D) Lateral schematic view of the olfactory system, in which is indicated the zonal limit reached on the septum by M72-expressing OSNs in Ac3+/+ mice; in blue is the corresponding limit reached in Ac3-/- animals. C, caudal; D, dorsal; L, lateral; M, medial; R, rostral; V, ventral.