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Figure 4


Fig. 4. The basement membrane is normal in Npnt-null embryos during kidney development. (A-F) Transverse sections through E11.5 Npnt+/+ and Npnt-/- embryos stained with antibodies against laminin (LN) or Collagen IV (COL IV). (G-L) Transverse sections through E13.5 Npnt+/+ and Npnt-/- embryos stained with antibodies against LN, COL IV or fibronectin (FN). Note the similar staining patterns in mutant and wild-type embryos. Scale bars, 50 µm. ND, nephric duct; UB, ureteric bud.