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Figure 1


Fig. 1. Removal of ß-catenin in renal vesicle progenitor cells causes reduced nephron formation in mice. (A) P1 kidneys from wild-type (left) and ß-catenin LOF mutant (right). White arrowheads point to the adrenal glands. (B-G) Histology of kidneys from LOF mutants of ß-catenin and proper controls at P1 (B-E) and at E13.5 (F,G). Six2TGC kidneys are slightly smaller than wild type. Scale bars: 0.5 mm in B-E, 0.1 mm in F,G. CD, collecting duct; NZ, nephrogenic zone; PA, pre-tubular aggregate; SB, S-shaped body.