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Figure 5


Fig. 5. Effect of Pitx3 overexpression on endogenous Ahd2 transcript levels and other mdDA marker genes. (A) Overexpression of Pitx3 in MN9D cells leads to an increase of endogenous Ahd2 transcript levels. Expression of Th, Aadc, Vmat2, Snca and Tbp were unaffected. (B) Densitometer-based quantification showing the fold change of endogenous transcripts between cells transfected with empty expression vector (+ Control, white bars) and Pitx3 transfected cells (+ Pitx3, black bars).