(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 7


Fig. 7. In Scx-/- mutant embryos, the endotenon cells fail to form a tendon sheath and are intermixed with the tenocytes in the FDP tendon. TEM (A,B) and antibody staining (C-G) of sections at the second digit phalange of wild-type (WT) and Scx-/- mouse embryos at E18.5. (A,B) TEM of the flexor digitorum profoundus (FDP) tendon amplified x550 to emphasize cellular aspects of the FDP. Green arrowheads, tenocytes; red arrowheads, the endotenon. (C,D) ScxGFP signal (green) and anti-EphA4 antibody (red) are overlaid on a DIC image of a cross section through the FDP tendon. (E-G) ScxGFP signal (green), and anti-tenascin C antibody (red) highlighting the endotenon in wild-type (E) and mutant (G,F) FDP tendon. Notice the collapse of the endotenon signal in the mutant tendon.