Fig. 2. Nkx2.2 is abnormally expressed ventrally, including in a small number of mDA progenitors, in Foxa1^-/-;Foxa2cko but not Foxa2cko or Foxa1^-/- embryos. (A-H') Coronal sections of mouse embryos. (A-D,A'-D') Lmx1a and Lmx1b are expressed normally in mDA progenitors of Foxa1^-/-, Foxa2cko and Foxa1^-/-;Foxa2cko mutants, as in control embryos. (E-H,E'-H') Nkx2.2 expression is expanded ventrally starting at E10.5. (I-L) A small number of Lmx1a⁺ Nkx2.2⁺ progenitors are observed in the ventral midbrain of Foxa1^-/-;Foxa2cko but not Foxa1^-/-, Foxa2cko and control embryos at E12.5. Scale bars: 75 µm.