Fig. 3. SoxN acts downstream of Der- and Wg-pathway activities to direct denticle formation. (A) Cuticle of a wg null mutant larva. (B) Cuticle phenotype of a wg;SoxN^U6-35 double-mutant larva; notice that removal of SoxN function largely rescues the wg mutant phenotype. (C-E) Removal of SoxN function rescues the pan mutant phenotype. (C) pan² mutant cuticle. (D) pan²;SoxN^U6-35/+ cuticle. (E) pan²;SoxN^U6-35 cuticle. (F) Cuticle of an scaGal4-UAS-Egfr^Act larva; note the ectopic denticles posterior to the wild-type row-6 denticles (indicated by arrows). (G) Cuticle of an scaGal4-UAS-Egfr^Act;SoxN^GA1192 larva; note that ectopic denticle formation is largely suppressed.