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Figure 1


Fig. 1. eIF4G2 encodes a novel eIF4G homolog in Drosophila.(A) Alignments of Drosophila eIF4G and eIF4G2 proteins with human eIF4GI (EIF4G1-HUGO) and eIF4GII (EIF4G3-HUGO). Black sections indicate recognized domains, with percentage identical to the eIF4GI middle domain marked. (B) Myc-eIF4E1 co-immunoprecipitates with HA-eIF4G2 from S2 cells. Immunoprecipitation with anti-HA. Western blot probed with anti-Myc and anti-HA, as indicated. Crude extract is 1/10 of each pre-immunoprecipitation (IP) sample.