Fig. 9. Isolation of mesDA progenitors from ES cell-derived neural populations. (A) Surface expression of Corin in undifferentiated ES cells and SDIA-induced populations. (B) RT-PCR analysis of unsorted SDIA-induced cells (all) and sorted Corin⁺ and Corin^- populations. Expression of undifferentiated ES cell-specific Nanog is not detected in the Corin⁺ population. (C) mesDA progenitors are enriched in the Corin⁺ population. Neurons generated from Corin⁺ cells show correct mesDA neuron identity. G3PDH, glyceraldehyde-3-phosphate dehydrogenase.