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Figure 7


Fig. 7. Peripheral nerve development in Sox10{Delta}K2/{Delta}K2 and Sox10aa1/aa1 embryos. Immunohistological analysis of spinal nerves from wild-type, Sox10{Delta}K2/{Delta}K2 and Sox10aa1/aa1 mouse embryos at 18.5 dpc was carried out using antibodies against NF165, Sox10, Oct6 and SoxB1 (Sox1/2/3). Expression of Mbp and Mpz was additionally visualized in all three genotypes by in situ hybridization with specific antisense probes.