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Figure 4


Fig. 4. The abnormalities of spermatogenesis in Brdt{Delta}BD1/{Delta}BD1 mice were apparent at the elongating spermatid stage. (A,B) PAS staining of histological sections of testes from wild-type (A) and Brdt mutant (B) mice showing the abnormal shape of the elongating spermatids (B; arrow). (C,D) Immunostaining of histological sections of testes from wild-type (C) and Brdt mutant (D) mice with anti-Prm1 antibody, showing that the expression of Prm1 appeared on schedule, although the morphogenesis of the spermatids was abnormal in the mutants. Scale bar: 40 µm.