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Figure 7


Fig. 7. Neuronal expression of NAB-1 is sufficient to rescue nab-1 polarity defects. (A) Wild type, nab-1 mutants and nab-1 mutants expressing NAB-1 from various promoters, and nab-1 mutants expressing the NAB-1-deletion constructs were subjected to unc-30 RNAi treatment. Images of the dorsal SNB-1::GFP vesicle clusters are shown. Diagram (bottom of A) shows NAB-1 deletions used. (B) Quantification of the number of ectopic dorsal SNB-1::GFP puncta per animal (n=15). P<0.001 (nab-1, Pmyo-3 NAB-1 and Punc-25 NAB-1{Delta}204-378 versus wild-type). Scale bar: 5 µm in A.