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Figure 2


Fig. 2. Haematoxylin-Eosin staining of fresh-frozen dorsal skin sections of control and K14-Gata3-/- mice. (A,B) P0: skin of K14-Gata3-/- is indiscernible from control skin. (C,D) P7: in K14-Gata3-/- HFs are disorganized and do not produce hairs. Epidermis is thickened. (E,F) P11: in the mutant, (abnormal) hairs are still not penetrating the epidermis. (G,H) P13: some irregularly formed hairs penetrate the skin; both dermis and subcutaneous fat layer (white cells) are much thinner in K14-Gata3-/- than in control skin. Scale bar in A: 50 µm for A,B; 200 µm for C-H.