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Figure 5


Fig. 5. Decidualization responses in wild-type and Dprp-null mice. (A,B) Gross appearance of artificially decidualized uteri from day 7.5 pseudopregnant wild-type (+/+) and Dprp-null (-/-) mice. (C) Day 7.5 pseudopregnant deciduoma weight responses from wild-type (+/+; n=7) and Dprp-null (-/-; n=9) mice. (D) Day 7.5 pseudopregnant deciduoma weight responses from wild-type (+/+; n=7) and Dprp-null (-/-; n=9) mice expressed by ratio to body weight. *, P<0.01. (E) Alkaline phosphatase (AP) activities of day 7.5 pseudopregnant deciduoma from wild-type (+/+; n=7) and Dprp-null (-/-; n=7) mice. (F) Immunocytochemical localization of DPRP in the day 7.5 pseudopregnant-decidualized uterus from wild-type (+/+) mice. (G) Immunocytochemical localization of GFP in the day 7.5 pseudopregnant-decidualized uterus from Dprp-null (-/-) mice. (H) GFP fluorescence in the day 7.5 pseudopregnant-decidualized uterus from Dprp-null (-/-) mice. The mesometrial region of the uterus is located at the top of each image. (I) Northern blot analysis of Dprp, Plp-j, Plp-b, Mt1 and Gapdh expression in deciduoma from day 7.5 pseudopregnant wild-type (+/+) and Dprp-null (-/-) mice. Scale bars: 1 mm.