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Figure 1


Fig. 1. {Delta}N89ß-catenin expression rescues alveologenesis in PR-/- mice during pregnancy. Carmine and X-Gal-stained wholemounts of transplanted glands at 8.5 (A-D) and 14.5 (E-H) days of pregnancy. PR-/- glands do not develop alveoli (A,E). By contrast, alveoli are observed in PR-/-;{Delta}N89ß-catenin glands (B,F) that are consistently more distended than in control PR+/- (C,G) and endogenous Rag1-/- glands (D,H). Scale bars: 200 µm.