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Figure 3


Fig. 3. Morphology of female virgin glands shows that {Delta}N89ß-catenin induces precocious development in the presence and absence of PR. Carmine-stained wholemounts of inguinal mammary glands from 12-week-old (A-D) and 26-week-old (E-H) virgin mice. Precocious development is not observed in PR+/- (A,E) or PR-/- (C,G) glands but is seen in PR+/-;{Delta}N89ß-catenin (B,F) and PR-/-;{Delta}N89ß-catenin (D,H) glands, respectively. LN, lymph node. Brackets (F,H) indicate the regions that are magnified in Fig. 4. Scale bars: 5 mm.