Development -- Hiremath et al. 134 (20): 3703 Figure IG6

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Fig. 6. A comparison of PR^+/-; ${Delta}$ N89ß-catenin and PR^-/-; ${Delta}$ N89ß-catenin glands. (A,C,E) PR^+/-; ${Delta}$ N89ß-catenin; (B,D,F) PR^-/-; ${Delta}$ N89ß-catenin. Hematoxylin and Eosin staining (A,B) shows that ${Delta}$ N89ß-catenin induces bilayered, secretion-filled structures. Note that alveolar lumen diameters are significantly larger in PR^-/-; ${Delta}$ N89ß-catenin glands. Functional alveolar differentiation is demonstrated by immunohistochemistry for casein expression (C,D) and Oil Red O staining (E,F) to detect lipid droplets in alveoli. (G) Average alveolar luminal area in PR^+/-; ${Delta}$ N89ß-catenin (gray) and PR^-/-; ${Delta}$ N89ß-catenin (black) glands. Scale bars: 50 µm.