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Figure 8


Fig. 8. Mis-expression of Sox10 generates ectopic vesicle that express otic vesicle genes. (A) GFP fluorescence in an embryo electroporated with a control-GFP vector. (B) Embryo in A hybridized with Notch1. (C) An embryo electroporated with a Sox10-GFP construct shows GFP-positive ectopic vesicles (arrows). (D) Embryo in C hybridized with a Notch1 probe. The ectopic vesicles (arrows) express Notch1. (E) An embryo electroporated with a Sox10-GFP construct shows GFP-positive ectopic vesicles (arrows). (F) Embryo in E hybridized with an EphA4 probe. The ectopic vesicles (arrows) express EphA4. (G) An embryo electroporated with a Sox10-GFP construct shows GFP-positive ectopic vesicles (arrows). (H) Embryo in G hybridized with a Spalt4 probe. The ectopic vesicles (arrows) express Spalt4.