Fig. 2. Neural induction by inhibitors of Smad1 and Smad2 signaling occurs in
the absence of the mesoderm in Xenopus. Double in situ
hybridizations showed that neural marker induction in embryos injected with
tActRIIB, Smad7 or Ski occurred in the absence of the mesodermal markers
Chordin and MyoD. The red speckled staining is from the injected lineage
tracer.