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Figure 4


Fig. 4. Reduced chondrocyte proliferation in Prx1-Hif1{alpha} digits. BrdU incorporation into forming digits of control (A) and Prx1-Hif1{alpha} (B) mice. (C) Quantification of BrdU incorporation reveals a 3.5-fold reduction in the percentage of dividing cells in the mutant (control, 20.99±1.65%; Prx-1-Hif1{alpha}, 5.94±0.62%. P<0.001, n=4).