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Figure 1


Fig. 1. Expression profile of L-R asymmetry markers within the chick genital ridges before and after sex determination. (Top three rows) Transverse sections stained for fibronectin (Fn, red), N-cadherin (N-Cad, red), and DMRT1 plus Fn (in green and red, respectively) at E5 (HH26-27), E7 (HH30-31) and E12 (HH38). At E5 and E7, ZZ and ZW embryos show similar L-R differences, and only sections from ZW embryos are shown. Arrows in the ZZ E12 panel highlight areas of the left epithelium that are still DMRT1-positive. (Bottom two rows) Expression of ER{alpha} (green) or ER{alpha} and LHX9 (red) at HH30-31 (left) and HH38 (right). L, left; R, right. Scale bars: 50 µm.