Fig. 4. Sens alone can both repress R7 and activate R8 features. Adult
cryosections from control and sens GOF Drosophila.
(A) IP-GAL4; UAS-lacZ; (B,D) yw67;
UAS-sens/CyO; TM2/TM6B; (C,I) IP-GAL4; Sp/CyO;
TM2/TM6B; (E-G,J-L) IP-GAL4; UAS-sens (H)
IP-GAL4; UAS-sens/CyO; TM2/TM6B. All retinas oriented dorsal left,
distal up; R7 and R8 layers are bracketed. Sections were stained for
ß-gal (purple, A), Rh3 (purple, B,C,F,G), Rh4 (green, B,F), Rh5 (green,
C,G; purple, D,H), Rh6 (green, D,H; purple, L), Sens (green, E,I-L) and Pros
(purple, I-K). Note that many sens-misexpressing R7 cells exhibit an
R8-like proximal nucleus (E,J-L). (M) Summary of control or
sens GOF phenotypes. `R7' represents sens-misexpressing R7
cells in sens GOF eyes.