(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 4


Fig. 4. Krm promotes LRP6-mediated Wnt signaling. (A-D) TOPFLASH luciferase reporter assays in HEK293T cells. Co, empty pCS2 vector. (A) XKrm1 cooperates specifically with LRP6. (B) Co-transfection of mesd and Xkrm1. (C) BMP luciferase reporter assay in HEK293T cells. (D) Effect of XKrm1 on LRP6 signaling is Dkk1-dependent. RLU, relative light units.