Fig. 8. Double Ttrap and Smad3b knockdown rescues CE defect in Ttrap
knockdown. myod marks paraxial/adaxial mesoderm (8 ss).
(A) Broadened somites and a wide distance between myod cells
in Ttrap single knockdown embryo. (B) A combination of 16 ng
TtrapMO and 1 ng Smad3bMO shows closer convergence of
myod cells at midline. However, somitic expression is still broad
relative to the fully rescued embryo co-injected with 2 ng Smad3bMO
(C), which now displays the normal myod domain. Dorsal views,
anterior at top.