Fig. 4. Microarray and RT-PCR analyses of gene expression in isolated seminiferous tubules from XX/Sry and XY W/W^v testes. (A,B) Microarray expression analysis showing the top 20 genes that were (A) downregulated and (B) up-regulated in XX/Sry testes. The fold change represents the difference in the expression level in seminiferous tubules between XX/Sry and XY W/W^v testes; fold change in parentheses showing the difference in expression level in whole testis. (C) RT-PCR analysis of genes selected from the top-20 genes that were up- and down-regulated in XX/Sry seminiferous tubules.