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Figure 2


Fig. 2. LRP6 and Wnt11 depletion cause similar effects on dorsal gene expression. The expression of Wnt target genes (siamois, Xnr3) assayed by real-time RT-PCR at stage E9.5-E10.25 in sibling embryos depleted of Wnt11 or LRP6. Expression of Wnt target genes was reduced in both cases, whereas that of Xvent1, Xvent2 and BMP4 were not.