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Figure 6


Fig. 6. HH-reporter expression in Shh null and Xt/Xt (Gli3) mutant embryos. (A-D) Expression of the del5-LacZ transgene in the limbs and in the neural tube of wild-type (A,C), Xt/Xt (B) and Shh null (D) embryos at E11.5. The expression level of del5-LacZ was reduced in Shh-/- (D) and augmented in Xt/Xt (B) mutant embryos (black arrows).