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Figure 7


Fig. 7. Shh null mutants have reduced HH signaling in the developing urogenital organs. A reduction in LacZ activity from the del5-LacZ reporter of Shh-/- mutant PCM and bladder (B,D) was observed when compared with the control specimen (A,C). (C,D) Higher magnifications of the boxed areas show the bladder primordia. b, bladder; c, cloaca; gt, genital tubercle; pcm, peri-cloacal mesenchyme; u, internal urethra; uc, umbilical cord.