Fig. 5. Morphology of the karussell-mutant neurons. Individual
neuroblasts were filled using the DiI methodology. (A,E)
DiI-labeled lineages of neuroblasts NB 3-5 and NB 7-3 in a wild-type embryo.
(A') Higher magnification of the dotted area in A. The arrowhead
denotes the growth cone. (B,F) Camera lucida drawings of
wild-type lineages of NB 3-5 and NB 7-3. (C,G) DiI-labeled
lineages of neuroblasts NB 3-5 and NB 7-3 in a hemizygous kus-mutant
embryo. (C') Higher magnification of the dotted area in C. The
arrowhead denotes the enlarged growth cone in the kus mutant.
(D,H) Camera lucida drawings of these preparations reveal
principally normal projection patterns, but altered fiber morphology and
enlarged growth cones. No ectopic crossing of the CNS midline was
observed.