Fig. 5. Notch2 mutant, Pax2-expressing early renal epithelia proliferate as wild-type, whereas Jag1-expressing, Notch2-deficient clusters have few cycling cells. (A,B) Representative images of BrdU incorporation (red) within the Jag1-expressing clusters (green) in wild type and mutant. (C,D) Histograms of results from several embryos indicate the percentage of BrdU-labeled cells within the Pax2- or Jag1-expressing domains. Data are presented as means±s.e.m. Scale bar: 0.05 mm.