Fig. 5. Arhgef11 function is important for proper otolith development.
(A,B) Otic vesicles of example embryos at
48 hpf showing
two or three otoliths (arrowheads). Scale bar, 50 µm. (C) Bar graph
of the percentage of WT control, MO-injected,
DHPH-overexpressing, and
mutant embryos with two otoliths in both otic vesicles, or with an abnormal
number (one or three) in at least one otic vesicle.