Fig. 5. kit is required during a late step in melanophore
development. Dorsal regions of late larval fish are shown before (A-D) and
after (A'-D') incubation with L-dopa. Arrowheads, sites of
melanoblasts before and after L-dopa treatment. (A,A') In
wild-type D. rerio, previously melanized melanophores are present
within the dorsal melanophore stripe and on dermal scales (arrow). Very few
L-dopa+ melanoblasts are revealed (arrowheads).
(B,B') kit mutant D. rerio exhibit more
undifferentiated melanoblasts than wildtype D. rerio.
(C,C') In wild-type D. albolineatus, many more
L-dopa+ melanoblasts are present than in wild-type D.
rerio. (D,D') kit mutant D.
albolineatus have similar numbers of L-dopa+ melanoblasts to
wild-type D. albolineatus.