Fig. 2. Characterization of SVZ-derived cultures from mice. In culture,
SVZ-derived cells prepared from WT mice (top panels) display
immunocytochemical markers of immature neurons (strongly positive for
ßIII-tubulin, GABA and PSA-NCAM). Neither genetic deletion of NCAM
(NCAM-/-, middle panels) nor the enzymatic removal of PSA
(WT+EndoN, bottom panels) affects the morphology or the pattern of markers
expressed by these cells. Scale bar: 20 µm.