Fig. 2. Expression of the Man1-lacZ reporter in embryos.
(A-C) Whole-mount lacZ staining in heterozygotes at stages
E8.5-11. (D-F) Sagittal sections showing expression of
Man1-lacZ in both embryonic and extraembryonic compartments.
(G) Frontal section showing expression of Man1-lacZ in the
CNS. (H,I) High magnification views of sections through the yolk
sac. Scale bars: 1 mm in A-G; 0.05 mm in H,I. al, allantois; bc, blood cells;
ce, cerebellum; ec, endothelial cells; epc, ectoplacental cone; fb, forebrain;
fg, foregut; fp, floor plate; fv, fourth vesicle; hb, hindbrain; ht, heart;
mb, midbrain; me, mesothelium; mv, medial vesicle; nf, neural fold; nt, neural
tube; pl, placenta; po, pons; s, somites; ve, visceral endoderm; ys, yolk
sac.